VIP Biography for
Allen B. Edmundson
 | Allen B. Edmundson |
| Industry | Research |
| Title | Member and Head of Crystallography Program |
| Expertise | Immunobiology, x-ray crystallography |
| Current Organization | Oklahoma Medical Research Foundation |
| Type of Organization | Private, nonprofit research foundation |
| Major Product | Medical research |
| Area of Distribution | International |
| University/Degree | A.B., Dartmouth College, NH, 1954; Medical Certificate, Dartmouth Medical School, NH, 1955; Ph.D., Rockefeller University, 1961 |
| Born | June 16, 1932, Flat River, Missouri |
| Honors & Awards | Summa Cum Laude; Phi Beta Kappa; Sigma Xi; M.E.R.I.T. Award, National Cancer Institute, N.I.H., the first such award at the University of Utah, 1986; First Visiting Research Scholar, University of Technology, Sydney, Australia, 1992; Named by the International Biographical Centre, Cambridge, England: 2000 Outstanding Scientists of the 20th Century, One Thousand Great Americans, Living Legends and Lifetime Achievement Award for Outstanding Contribution to Biochemistry and Crystallography; Honors from the American Biographical Institute, Raleigh, NC: Five Hundred Leaders of Influence, Twentieth Century Achievement Award, One of Greatest Minds of the 21st Century and Leading Intellectuals of the World, The Genius Elite |
| Published Works | Over 100 publications: "Amino-acid sequence of sperm whale myoglobin", Nature, 1965; co-author, "Rotational allomerism and divergent evolution of domains in immunoglobulin light chains", Biochemistry, 1975; Scientific American, 1977; co-author with G. Tribbick, T, Mason and M. Geyson, "Similar binding properties of peptide ligands for a human immunoglobulin and its light chain dimer", Molecular Immunology, 1989; co-author, "Treatment of osteoarthritis with aspartame", Clinical Pharmacology Therapeutics, 2000; "Reminiscences" of A.B.E., Journal of Molecular Recognition, 2002 |
| Hobbies & Sports | Basketball, tennis, softball, cricket, English cathedrals |
| Career Accomplishments | Worked with Sir John C. Kendrew in a Nobel Prize winning project, "Structure of Myoglobin," the sequence of this protein was used to calibrate automated amino acid sequencers for 25 years; Solved one of the first 3-D structures of an antibody fragment and many more since; Introduced and proved concept of induced fit mechanisms of antigen binding by antibodies; Identified aspartame "Equal" as a therapeutic analgesic for humans; Helped develop contemporary field of combinatorial chemistry |
| Work History | U.S.P.H.S., Postdoctorate Fellow, Lab. of Molecular Biology, Cambridge, 1960-64; Associate Biochemist, 1964-72, Senior Biochemist, 1972-76, Argonne Nat'l Lab.; Sabbatical leave in the lab. of H.C. Watson, Dept. of Biochemistry, Univ. of Bristol, England, 1970-71; Prof. of Biology and Biochemistry, Univ. of UT, 1976-89; Avery Rush, Junior Chair of Macromolecular Crystallography and Immunology, Harrington Cancer Center, 1989-95; Adjunct Prof. of Biochemistry and Biophysics, TX A&M Univ., 1991-present; Associate Editor, Journal of Molecular Recognition, 1998-present |
| Children | Kathryn L. Edmundson, 45; Carole E. Detherage, 41; Douglas A. Edmundson, (deceased, 2002) |
| Spouse | Shelagh Bowman-Edmundson |
| Married | August 8, 1987 |
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